Evidaxis

Foldseek

repo
AI Drug Discovery · n = 19 · steineggerlab/foldseek
Tracked · conf medium
momentum
momentum 35.5 of 100 35.5 /100
momentum
35.5/100
pctile
p11
convergence gate
Convergence gate: gate shut × ×
gate
0 of 2 axes

gate shut.

gate shut
position in cohort distribution one of 19 in cohort
percentile 11 within cohort p25 p50 p75 p0 p100
percentile
p11
momentum is the combined velocity and citation signal, percentile within cohort
velocity z
velocity z gaugevelocity z-2.99 within cohort, log-slope -0.046/wk.0-2.99
velocity z
-2.99 σ
slope
-0.046/wk
log-slope -0.046/wk
convergence planefull gate = rising
Foldseek on the convergence plane Foldseek at velocity z -2.99 and citation z +0.66, against 13 dual-axis cohort peers. neither axis clears the Rising gate (z>=1 + positive slope). z>=1 median velocity z → citation z ↑ AlphaFold3: velocity z -0.56, citation z +0.42 Boltz: velocity z -2.58, citation z +2.07 DeepChem: velocity z +2.96, citation z -0.73 DiffDock: velocity z +0.01, citation z -0.35 ESM / ESMFold: velocity z -0.03, citation z +0.49 gnina: velocity z +2.86, citation z -0.35 Graphormer: velocity z +0.99, citation z -0.23 OpenFold: velocity z -0.02, citation z -0.41 ProteinMPNN: velocity z +0.00, citation z -0.51 RFdiffusion: velocity z +0.66, citation z +0.09 SaProt: velocity z -1.85, citation z +1.10 TorchDrug: velocity z +0.01, citation z -0.18 Uni-Mol: velocity z +0.01, citation z +0.54 Foldseek
velocity z
-2.99
citation z
+0.66
peers
18

neither axis clears the Rising gate (z>=1 + positive slope).

citation z
citation z gaugecitation z+0.66 within cohort, log-slope +1.571/yr.0+0.66
citation z
+0.66 σ
slope
+1.571/yr
log-slope +1.571/yr
cohort
19
systems measured
weekly commits
0.1
not rising
total citations
2,485
present
momentum
35.5
percentile p11
commit heatmap, last 26 weeks0.1/wk
weekly commits, 26 weeks26 weeks of commits, peak 9 in a week, 7 active weeks, 22 total.week 1: 3 commitsweek 2: 3 commitsweek 3: 0 commitsweek 4: 4 commitsweek 5: 9 commitsweek 6: 1 commitsweek 7: 0 commitsweek 8: 0 commitsweek 9: 0 commitsweek 10: 0 commitsweek 11: 0 commitsweek 12: 0 commitsweek 13: 0 commitsweek 14: 1 commitsweek 15: 0 commitsweek 16: 0 commitsweek 17: 0 commitsweek 18: 0 commitsweek 19: 0 commitsweek 20: 0 commitsweek 21: 1 commitsweek 22: 0 commitsweek 23: 0 commitsweek 24: 0 commitsweek 25: 0 commitsweek 26: 0 commits
weeks
26
peak/wk
9
active
7
total
22
citations by yeartotal 2,485
Citations by year2012: 1, 2021: 1, 2022: 23, 2023: 222, 2024: 658, 2025: 982, 2026: 598. Total 2485 citations.2012: 1 citations1212021: 1 citations2112022: 23 citations22232023: 222 citations232222024: 658 citations246582025: 982 citations259822026: 598 citations26598
total cites
2485
years
7
latest yr
598

Foldseek holds an Evidaxis momentum score of 35.5 of 100 on methodology m2, snapshot 2026-08-08, measured within the AI Drug Discovery cohort (n = 19). No axis is currently rising within the cohort, so it sits below the two-axis gate.

Derived signals

second-order reads, computed from the published series

Three signals ship when the commit series is statistically sufficient; the rest are held in a reserved state until the data supports them. A reserved signal shows its reason, never a fabricated number. How these are computed.

recency-weighted swing trailing 13-week vs prior 39-week log-slope ratio +0.76, regime decelerating. prior slope -0.025, recent slope -0.019 per week. -0.025prior 39w-0.019recent 13w+0.76×
swing
+0.76×
regime
decelerating
windows
13w vs 39w
snapshot 1 of 1 · · m2
commit-axis Sharpe log-linear slope over residual std, value -0.038 with 95% CI -0.060 to -0.016, 50 degrees of freedom. CI spans zero.0-0.03895% CI -0.060, -0.016-0.060-0.016
sharpe
-0.038
95% ci
-0.060, -0.016
dof
50
snapshot 1 of 1 · · m2
commit changepoint52 weekly commit points. No significant changepoint detected (|delta slope| within the noise floor).no significant changepoint
changepoint
none detected
snapshot 1 of 1 · · m2
code-leads-citation lag reserved

reserved: citation series too short / axis absent for cross-correlation

status
reserved
value
insufficient data
snapshot 1 of 1 · · m2
axis alpha vs cohort reserved

reserved: cohort N too small for regression (power ~0)

status
reserved
value
insufficient data
snapshot 1 of 1 · · m2
gate ETA reserved

reserved: needs snapshot history (1 snapshot exists)

status
reserved
value
insufficient history
snapshot 1 of 1 · · m2
methodology gate snapshot 1 of 1 · · m2
commit weeks
52
citation years
7
shipped
3
reserved
3

shipped

  • recency-swing
  • commit-sharpe
  • commit-changepoint

reserved

  • code-leads-citation-lag
  • axis-alpha
  • gate-eta
snapshot 1 of 1 · · m2

Verdict

Foldseek is tracked. No axis is currently rising relative to its cohort.

Path to Rising: needs development velocity to recover (at least 5 commits per week and a positive within-cohort slope); citation momentum to turn positive within its cohort.

Sources

steineggerlab/foldseek development-velocity axis
OpenAlex paper citation-momentum axis

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Evidaxis tracked, Foldseek
[![Evidaxis: Foldseek](https://evidaxis.org/badge/e_R2TJDSZX29K/2026-w32.svg)](https://evidaxis.org/e/e_R2TJDSZX29K)

Others in AI Drug Discovery

AlphaFold3 AI Drug Discovery
Calibration
49
p50
vel -0.56 cit +0.42
axis dials
-0.56 +0.42
BioEmu AI Drug Discovery
Single-axis
88
p100
vel +3.02 cit no axis
axis dials
+3.02 n/a
Boltz AI Drug Discovery
Watch
47
p22
vel -2.58 cit +2.07
axis dials
-2.58 +2.07
Chai-1 AI Drug Discovery
Single-axis
30
p6
vel -1.62 cit no axis
axis dials
-1.62 n/a
DeepChem AI Drug Discovery
Tracked
64
p89
vel +2.96 cit -0.73
axis dials
+2.96 -0.73
DiffDock AI Drug Discovery
Tracked
48
p39
vel +0.01 cit -0.35
axis dials
+0.01 -0.35

Full AI Drug Discovery cohort →

entity_id e_R2TJDSZX29K methodology m2 snapshot 035a72a81e59 period 2026-w32 record JSON ↓ source snapshot

Score derived from public data on Evidaxis methodology m2, never edited by hand. Cite as: “Evidaxis, Foldseek, entity e_R2TJDSZX29K, snapshot 2026-w32.”

Durable reference (format-independent): urn:evidaxis:claim:e_R2TJDSZX29K:m2:2026-08-08