Evidaxis

Foldseek

repo
AI Drug Discovery · n = 19 · steineggerlab/foldseek
2 of 3 axes measurable · conf medium
convergence gate
Convergence gate: Gate: computed weekly across the cohort; no convergence event this week Development velocity: measured × Citation momentum: measured × Direct-dependents momentum (deps.dev): not measurable ∅
gate
0 of 3 axes

Gate: computed weekly across the cohort; no convergence event this week

Gate: computed weekly across the cohort; no convergence event this week
position in cohort distribution one of 19 in cohort
percentile 94 within cohort p25 p50 p75 p0 p100
percentile
p94
momentum averages present-axis z-scores; two- and three-axis scores are not strictly comparable
velocity z
velocity z gaugevelocity z+2.89 within cohort, log-slope +0.026/wk.0+2.89
velocity z
+2.89 σ
slope
+0.026/wk
log-slope +0.026/wk
citation z
citation z gaugecitation z+0.65 within cohort, log-slope +1.571/yr.0+0.65
citation z
+0.65 σ
slope
+1.571/yr
log-slope +1.571/yr
direct-dependents z Direct-dependents axis: minimum of 14 clean points and 5 latest dependents not met.
cohort
19
systems measured
weekly commits
2.5
Development velocity axis: measured.
total citations
2,617
Citation axis: measured.
momentum
72.2
percentile p94
commit heatmap, last 26 weeks2.5/wk
weekly commits, 26 weeks26 weeks of commits, peak 18 in a week, 11 active weeks, 45 total.week 1: 0 commitsweek 2: 0 commitsweek 3: 0 commitsweek 4: 1 commitsweek 5: 0 commitsweek 6: 0 commitsweek 7: 7 commitsweek 8: 0 commitsweek 9: 0 commitsweek 10: 0 commitsweek 11: 3 commitsweek 12: 1 commitsweek 13: 2 commitsweek 14: 1 commitsweek 15: 0 commitsweek 16: 0 commitsweek 17: 0 commitsweek 18: 0 commitsweek 19: 0 commitsweek 20: 6 commitsweek 21: 18 commitsweek 22: 4 commitsweek 23: 1 commitsweek 24: 1 commitsweek 25: 0 commitsweek 26: 0 commits
weeks
26
peak/wk
18
active
11
total
45
citations by yeartotal 2,617
Citations by year2012: 1, 2021: 1, 2022: 23, 2023: 222, 2024: 659, 2025: 981, 2026: 730. Total 2617 citations.2012: 1 citations1212021: 1 citations2112022: 23 citations22232023: 222 citations232222024: 659 citations246592025: 981 citations259812026: 730 citations26730
total cites
2617
years
7
latest yr
730

Foldseek holds an Evidaxis momentum score of 72.2 of 100 on methodology m3, snapshot 2026-09-26, measured within the AI Drug Discovery cohort (n = 19). Axis coverage: 2 of 3 axes measurable. Gate: computed weekly across the cohort; no convergence event this week

Derived signals

second-order reads, computed from the published series

Three signals ship when the commit series is statistically sufficient; the rest are held in a reserved state until the data supports them. A reserved signal shows its reason, never a fabricated number. How these are computed.

recency-weighted swing trailing 13-week vs prior 39-week log-slope ratio -1.66, regime recent slope sign differs from prior window. prior slope -0.023, recent slope +0.038 per week. -0.023prior 39w+0.038recent 13w-1.66×
swing
-1.66×
regime
recent slope sign differs from prior window
windows
13w vs 39w
snapshot 1 of 1 · · m3
commit-axis Sharpe log-linear slope over residual std, value -0.017 with 95% CI -0.042 to +0.009, 50 degrees of freedom. CI spans zero.0-0.01795% CI -0.042, +0.009-0.042+0.009
sharpe
-0.017
95% ci
-0.042, +0.009
dof
50
snapshot 1 of 1 · · m3
commit changepoint52 weekly commit points. Changepoint at week 5 (2025-11-01), slope change -3.931 commits per week.2025-11-01
date
week
5 of 52
Δslope
-3.931/wk
snapshot 1 of 1 · · m3
code-leads-citation lag reserved

reserved: citation series too short / axis absent for cross-correlation

status
reserved
value
insufficient data
snapshot 1 of 1 · · m3
axis alpha vs cohort reserved

reserved: cohort N too small for regression (power ~0)

status
reserved
value
insufficient data
snapshot 1 of 1 · · m3
gate ETA reserved

reserved: needs snapshot history (1 snapshot exists)

status
reserved
value
insufficient history
snapshot 1 of 1 · · m3
methodology gate snapshot 1 of 1 · · m3
commit weeks
52
citation years
7
shipped
3
reserved
3

shipped

  • recency-swing
  • commit-sharpe
  • commit-changepoint

reserved

  • code-leads-citation-lag
  • axis-alpha
  • gate-eta
snapshot 1 of 1 · · m3

Measurement states

Foldseek is under weekly measurement. History: 13 weekly observations; minimum 4. Development velocity axis: measured. Citation axis: measured. Direct-dependents axis: minimum of 14 clean points and 5 latest dependents not met. Gate: computed weekly across the cohort; no convergence event this week

Sources

steineggerlab/foldseek development-velocity axis
OpenAlex paper citation-momentum axis

Others in AI Drug Discovery

AlphaFold3 AI Drug Discovery
2 of 3 axes measurable
51
p61
vel -0.23 cit +0.40 deps no axis
axis dials
-0.23 +0.40 n/a
BioEmu AI Drug Discovery
1 of 3 axes measurable
85
p100
vel +2.78 cit no axis deps no axis
axis dials
+2.78 n/a n/a
Boltz AI Drug Discovery
2 of 3 axes measurable
46
p28
vel -2.76 cit +2.04 deps no axis
axis dials
-2.76 +2.04 n/a
Chai-1 AI Drug Discovery
1 of 3 axes measurable
13
p0
vel -2.98 cit no axis deps no axis
axis dials
-2.98 n/a n/a
DeepChem AI Drug Discovery
3 of 3 axes measurable
61
p83
vel +3.38 cit -0.73 deps +0.00
axis dials
+3.38 -0.73 +0.00
DiffDock AI Drug Discovery
2 of 3 axes measurable
48
p44
vel -0.05 cit -0.35 deps no axis
axis dials
-0.05 -0.35 n/a

Full AI Drug Discovery cohort →

Direct-dependents momentum (deps.dev)

Direct-dependents axis: minimum of 14 clean points and 5 latest dependents not met.

Coverage state
below_floor
Cohort z
no axis
OLS slope
n/a
Theil-Sen slope
n/a
Latest direct dependents
n/a
Confirmed-clean points
0
Reconstructed history points
n/a
As-of partition
n/a
Fragility veto
n/a
Rising vote
no

Source: deps.dev (Google), CC-BY 4.0. Modified: aggregated to system-level counts and momentum scores.

Axis definition · Snapshot axis correlations

entity_id e_R2TJDSZX29K methodology m3 snapshot 9d2fe956adbc period 2026-w39 record JSON ↓ source snapshot

Score derived from public data on Evidaxis methodology m3, never edited by hand. Cite as: “Evidaxis, Foldseek, entity e_R2TJDSZX29K, snapshot 2026-w39.”

Durable reference (format-independent): urn:evidaxis:claim:e_R2TJDSZX29K:m3:2026-09-26